Phenotype Image Detail

Image

Caption

Stained cryo-sections of P30 wild-type (WT), heterozygous Rho^tm2.1Kpal (EK) and Rho^tm2.1Kpal/Rho^tm2.1Kpal (KK) mouse retinas. Staining of retinas with lectin PNA and DAPI revealed reduced thickness of rod photoreceptor cell layers in KK mouse retina, but the number of cone photoreceptor cells labeled by PNA was not reduced at this age. OS, photoreceptor outer segment; IS, photoreceptor inner segment; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer. Scale bar, 40 um.

Copyright

This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158

Associated Alleles

Symbol	Name
Rho^tm2.1Kpal	rhodopsin; targeted mutation 2.1, Krzysztof Palczewski

Associated Genotypes

Allelic Composition	Genetic Background
Rho^tm2.1Kpal/Rho^tm2.1Kpal	involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac