Phenotype Image Detail

Image

Caption

(E) Vestibular macula preparations stained with phalloidin-Alexa Fluor 488 to visualize actin-rich structures, including stereocilia and (F) Mid-turn organ of Corti preparations from Srrm4^bv/Srrm4⁺ (bv/+), Srrm4^bv/Srrm4^bv (bv/bv), and Srrm4^bv/Srrm4^bv Tg(Myo7a-Srrm4)#Bban/0 (bv/bv:Tg) mice stained with an anti-Myo7a antibody, which labels specifically the inner hair cells (IHCs) (arrows) and outer hair cells (OHCs) (brackets). Only the IHC row is affected by the bv mutation. Scale bars: 50 um.

Copyright

This image is from Nakano Y, PLoS Genet 2012;8(10):e1002966, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:193641

Associated Alleles

Symbol	Name
Srrm4^bv	serine/arginine repetitive matrix 4; Bronx waltzer
Tg(Myo7a-Srrm4)#Bban	transgene insertion, Botond Banfi

Associated Genotypes

Allelic Composition	Genetic Background
Srrm4^bv/Srrm4^bv	Not Specified
Srrm4^bv/Srrm4^bv Tg(Myo7a-Srrm4)#Bban/0	Not Specified