Phenotype Image Detail

Image

Caption

(A and B) Fourteen-month-old wild-type (A) and 14-month-old mt-Nd6^m3Dwa mouse retrobulbar optic nerves at 2,000X magnification. Several swollen axons with thin myelin (asterisks) can be seen adjacent to normal caliber axons (Lower Left) from a 14-month-old mutant mouse.

Copyright

This image is from Lin CS, Proc Natl Acad Sci U S A 2012 Dec 4;109(49):20065-70. Copyright 2012 National Academy of Sciences, U.S.A. J:192260

Associated Alleles

Symbol	Name
mt-Nd6^m3Dwa	mitochondrially encoded NADH dehydrogenase 6; mutation 3, Douglas C Wallace

Associated Genotypes

Allelic Composition	Genetic Background
mt-Nd6^m3Dwa	B6.129S-mt-Nd6^m3Dwa