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Caption | Ultrastructural analysis of optic nerve showing mitochondrial abnormalities in mt-Nd6m3Dwa mice. Quantification of mitochondria by transmission electron microscopy (EM) (4,000X). (A) The arrow indicates an axon of 14-month-old mt-Nd6m3Dwa mouse characterized by mitochondrial proliferation and marked thinning of the myelin sheath. (D) Abnormal mitochondrial morphology as seen with central vacuolization (arrow) and disrupted cristae (asterisks) in 14-month-old mutant. | ||||
Copyright | This image is from Lin CS, Proc Natl Acad Sci U S A 2012 Dec 4;109(49):20065-70. Copyright 2012 National Academy of Sciences, U.S.A. J:192260 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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