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Phenotype Image Detail
Image
Caption Ultrastructural analysis of retinal ganglion cells axonal morphology in 24-month-old mt-Nd6m3Dwa mice. Electron microscopic images of retrobulbar optic nerves of 24-month-old wild-type (A) and mutant (B) mice at 2,000X magnification. Retinal ganglion cells (RGC) axons in mutant mice were much more swollen and irregular in diameters and shapes.
Copyright This image is from Lin CS, Proc Natl Acad Sci U S A 2012 Dec 4;109(49):20065-70. Copyright 2012 National Academy of Sciences, U.S.A. J:192260
Associated
Alleles
Symbol Name
mt-Nd6m3Dwa mitochondrially encoded NADH dehydrogenase 6; mutation 3, Douglas C Wallace
Associated
Genotypes
Allelic Composition Genetic Background
mt-Nd6m3Dwa B6.129S-mt-Nd6m3Dwa
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory