Phenotype Image Detail

Image

Caption

Differential interference contrast microscopy of tectorial membranes (TMs). Images of the upper (A and B) and lower (C and D) surfaces of unfixed, Alcian blue-stained TMs from the basal end of the cochlea of Otoa^tm1Gpr/Otoa⁺ (Otoa^+/EGFP; A and C) and Otoa^tm1Gpr/Otoa^tm1Gpr (Otoa^EGFP/EGFP; B and D) mice at 7 weeks of age. Covernet fibrils (arrowheads) and radial collagen fibrils (arrows) are visible in mice of both genotypes. Hensen's stripe (HS) is not visible in the homozygous mutant mice. (Scale bar: 20 um.)

Copyright

This image is from Lukashkin AN, Proc Natl Acad Sci U S A 2012 Nov 20;109(47):19351-6. Copyright 2012 National Academy of Sciences, U.S.A. J:192263

Associated Alleles

Symbol	Name
Otoa^tm1Gpr	otoancorin; targeted mutation 1, Guy P Richardson

Associated Genotypes

Allelic Composition	Genetic Background
Otoa^tm1Gpr/Otoa^tm1Gpr	involves: 129S/SvEv