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Phenotype Image Detail
Image
Caption A representative P180-treated female Pomctm2Low/Pomctm2Low Tg(CAG-cre/Esr1*)5Amc/0 mouse before (left) and 8 weeks after (right) treatment with tamoxifen (TAM) illustrating the marked loss of body mass.
Copyright This image is from Bumaschny VF, J Clin Invest 2012 Nov 1;122(11):4203-12 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194013
Associated
Alleles
Symbol Name
Pomctm2Low pro-opiomelanocortin-alpha; targeted mutation 2, Malcolm J Low
Tg(CAG-cre/Esr1*)5Amc transgene insertion 5, Andrew P McMahon
Associated
Genotypes
Allelic Composition Genetic Background
Pomctm2Low/Pomctm2Low
Tg(CAG-cre/Esr1*)5Amc/0 		involves: 129S4/SvJae * C57BL/6 * CBA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory