Phenotype Image Detail

Image

Caption

Representative sections of Peyer's patches from wild-type (SPPL2a+/+) and Sppl2a^tm1Basc/Sppl2a^tm1Basc (SPPL2a-/-) mice were stained with hematoxylin and eosin or used for immunohistochemical visualization of B220+ B cells. The B cell deficiency is reflected in atrophic Peyer's patches. Bars, 500 um.

Copyright

This image is from Schneppenheim J, J Exp Med 2013 Jan 14;210(1):41-58, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:194664

Associated Alleles

Symbol	Name
Sppl2a^tm1Basc	signal peptide peptidase like 2A; targeted mutation 1, Bernd Schroder

Associated Genotypes

Allelic Composition	Genetic Background
Sppl2a^tm1Basc/Sppl2a^tm1Basc	involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl