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Caption | Spinal cord and dorsal root ganglion (DRG). (A, B) Transverse sections of the lumbar spinal cord of wild-type (WT) and Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve (BLAD) mice at E18.5. Lumbar motoneurons in the spinal cord, sensory neurons in the DRG and the size of DRG are markedly reduced in BLAD mice at E18.5. (C, D) Peripheral nerves (N) from E18.5 WT (C) and BLAD (D) embryos in a lumbar region. The lightly stained regions contain axons and the dark cells in the nerve (arrows) are presumptive Schwann cells. (E) Values (Mean +/- SD) for neuron numbers for WT and heterozygous (HET) mice did not differ and have been combined for comparison with homozygous mice. DRG, dorsal root ganglion; n, nerve; dotted line encloses motoneurons in the ventral horn. | ||||
Copyright | This image is from Hicks AN, PLoS One 2012;7(10):e47869, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:192196 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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