Phenotype Image Detail

Image

Caption

Electron micrograph of brown adipocytes (H) of adipocyte-specific Sqstm1^tm2.1Jmos/Sqstm1^tm2.1Jmos Tg(Fabp4-cre)1Rev/0 (KO) and wild-type (WT) mice. Brown adipocytes contain mitochondria with fewer cristae, which are also shorter and displaced to the periphery with varying degrees of disorientation. Scale bars:1 um (H, original magnification x4,000); 200 nm (H; original magnification, x25,000).

Copyright

This image is from Muller TD, J Clin Invest 2013 Jan 2;123(1):469-78 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194291

Associated Alleles

Symbol	Name
Sqstm1^tm2.1Jmos	sequestosome 1; targeted mutation 2.1, Jorge Moscat
Tg(Fabp4-cre)1Rev	transgene insertion 1, Ronald M Evans

Associated Genotypes

Allelic Composition	Genetic Background
Sqstm1^tm2.1Jmos/Sqstm1^tm2.1Jmos Tg(Fabp4-cre)1Rev/0	Not Specified