Phenotype Image Detail

Image

Caption

H&E staining of skin and lung tissue in a 3-month-old Cd28^tm1Ltu/Cd28^tm1Ltu Foxp3^{tm4(YFP/icre)Ayr}/Foxp3⁺ (Cd28^fl/fl x Foxp3^YFP-Cre) mouse. Histological analysis showed marked lymphocytic infiltration of skin and lung. Original magnification, X400.

Copyright

This image is from Zhang R, J Clin Invest 2013 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194503

Associated Alleles

Symbol	Name
Cd28^tm1Ltu	CD28 antigen; targeted mutation 1, Laurence A Turka
Foxp3^tm4(YFP/icre)Ayr	forkhead box P3; targeted mutation 4, Alexander Y Rudensky

Associated Genotypes

Allelic Composition	Genetic Background
Cd28^tm1Ltu/Cd28^tm1Ltu Foxp3^tm4(YFP/icre)Ayr/Foxp3^+	involves: 129S1/Sv * 129X1/SvJ * C57BL/6