Phenotype Image Detail

Image

Caption

Altered cornification and epidermal differentiation. A, B, C. Dorsal skin was sectioned and stained with hematoxylin and eosin. Slc27a4^pskn/Slc27a4^pskn (Mutant) epidermis was notably thicker and hyperkeratotic compared to the control (A, B, black bars are identical lengths), and had significantly fewer hair follicles. Higher magnifications (B, C) show thicker stratum corneum (SC) and changes in keratohyalin granules in the stratum granulosum (SG) (white arrows). Abbreviations: stratum basale (SB), stratum spinosum (SS).

Copyright

This image is from Tao J, PLoS One 2012;7(11):e50634, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:194779

Associated Alleles

Symbol	Name
Slc27a4^pskn	solute carrier family 27 (fatty acid transporter), member 4; pigskin

Associated Genotypes

Allelic Composition	Genetic Background
Slc27a4^pskn/Slc27a4^pskn	involves: FVB