Phenotype Image Detail

Image

Caption

Hair follicle and interfollicular epidermis hyperplasia in tamoxifen treated Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} (kDKO(P1)) mice. Representative histological analyses of H&E-stained skin sections from control (without tamoxifen) and kDKO(P1) mice sacrificed on the indicated day after birth. The middle and right columns of panels are higher magnification images of the left column of panels. Bar, 400 um (left columns); 40 um (middle columns); 100 um (right columns). Data are representative of more than 10 mice/group/sacrifice day.

Copyright

This image is from Nishio M, J Clin Invest 2012 Dec 3;122(12):4505-18 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193981

Associated Alleles

Symbol	Name
Mob1a^tm1.1Asuz	MOB kinase activator 1A; targeted mutation 1.1, Akira Suzuki
Mob1b^Gt(CC0690)Wtsi	MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute
Tg(KRT14-cre/ERT)20Efu	transgene insertion 20, Elaine Fuchs

Associated Genotypes

Allelic Composition	Genetic Background
Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^Gt(CC0690)Wtsi/Mob1b^Gt(CC0690)Wtsi Tg(KRT14-cre/ERT)20Efu/0	involves: 129P2/OlaHsd * C57BL/6 * CD-1