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Caption | Hydrocephalus in Jam3tm1Rha/Jam3tm1Rha C57BL/6 (JAM-C-/-) mice is accompanied by reactive gliosis. Immunostaining for glial fibrillary acidic protein (GFAP) reveals reactive gliosis in mutant mice. Mutant mice (symptomatic hydrocephalus score 1 shown here) exhibit extensive gliosis in the cortex (C and D) and hippocampus (G and H) as compared to wild-type (WT) littermates (A, B, E and F). In the cerebellum of mutants, only a mild increase of GFAP staining could be observed (K and L) as compared to WT cerebellum (I and J). Bars as indicated. | ||||
Copyright | This image is from Wyss L, PLoS One 2012;7(9):e45619, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191990 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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