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Caption | Hydrocephalus in Jam3tm1Rha/Jam3tm1Rha C57BL/6 (JAM-C-/-) mice is accompanied by loss of cortical layering. Immunostaining for neurofilament (NF) together with Tuj1 reveals loss of cortical layering in mutant mice (hydrocephalus score 1 shown; C and D) when compared to wild-type (WT) littermates (A and B). Inserts in B and D show pyramidal cells. Note that in the mutant mice no axonal and dendritic processes are visible. In contrast, the overall structure of the hippocampus (E and G) and the cerebellum (F and H) of mutant mice did not show any detectable alterations in NF/Tuj1 positive cells when compared to WT littermates. Bars as indicated. | ||||
Copyright | This image is from Wyss L, PLoS One 2012;7(9):e45619, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191990 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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