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Caption | Hydrocephalus in Jam3tm1Rha/Jam3tm1Rha (Jam-C-/-) mice is accompanied by hemorrhages. A: Hematoxylin and eosin staining showing signs of fresh (asterisk) and elder (arrows) bleedings within the III. ventricle. Elder bleedings consisted of erythrophages, hemosiderophages and also haematoidin pigment, the latter indicating bleedings older than 8 days (original magnification: 10X). B: Signs of elder bleedings were also observed within the aqueduct (arrow indicating hemosiderophage; HE stain; original magnification: 40X). C: Fresh and elder hemorrhages were also seen in the perivascular spaces (arrow) and within the central nervous system (CNS) tissue (asterisk) (HE stain; original magnification 10X). D: Iron staining indicating the presence of abundant intraparenchymal iron-loaden macrophages (original magnification: 40X). E, F: Subarachnoidal hemorrhages presenting with areas of fresh (E; arrows; HE staining; original magnification: 10X) and elder bleedings (F; iron staining; original magnification: 40X). | ||||
Copyright | This image is from Wyss L, PLoS One 2012;7(9):e45619, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191990 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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