Phenotype Image Detail

Image

Caption

In vivo foam cell analysis. Peritoneal macrophages (MPhi) harvested by lavage from Apoe^tm1Unc/Apoe^tm1Unc (11betaHSD1^+/+) (left upper and lower images) and Apoe^tm1Unc/Apoe^tm1Unc Hsd11b1^tm1Lex/Hsd11b1^tm1Lex (11betaHSD1^-/-) (right upper and lower images) mice stained with oil red O and hematoxylin. Magnification of top images 40X and lower images 100X. Data are pooled from two independently run studies. Significance vs. control: *p<=0.05.

Copyright

This image is from Garcia RA, PLoS One 2013;8(2):e53192, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199430

Associated Alleles

Symbol	Name
Apoe^tm1Unc	apolipoprotein E; targeted mutation 1, University of North Carolina
Hsd11b1^tm1Lex	hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Lexicon Genetics

Associated Genotypes

Allelic Composition	Genetic Background
Apoe^tm1Unc/Apoe^tm1Unc Hsd11b1^tm1Lex/Hsd11b1^tm1Lex	B6.129-Hsd11b1^tm1Lex Apoe^tm1Unc