Phenotype Image Detail

Image

Caption

B-cell lymphoma formation in the tissues of aged Polg^tm1Jiha/Polg⁺ (+/m, heterozygous mutator) mice. (A) Gross necropsy of tissues of moribund mice. Left and right panels represent a wild-type mouse without tumors and a moribund Polg^tm1Jiha/Polg⁺ mouse with tumors, respectively. Sp, spleen; Li, liver; LN, lymph node. Scale bars represent 1 cm.

Copyright

This image is from Mito T, PLoS One 2013;8(2):e55789, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199416

Associated Alleles

Symbol	Name
Polg^tm1Jiha	polymerase (DNA directed), gamma; targeted mutation 1, Jun-Ichi Hayashi

Associated Genotypes

Allelic Composition	Genetic Background
Polg^tm1Jiha/Polg^+	involves: C57BL/6JJcl