Phenotype Image Detail

Image

Caption

Anaemia in Lig1^m1Anu/Lig1^m1Anu mutants. (A) A Lig1^m1Anu/Lig1^m1Anu mutant (mut) with pale orange liver (arrow) compared to the red hemoglobin rich liver of a wild-type (wt) littermate. (B,C) Analysis of peripheral blood in E13.5 embryos by cytospin and Giemsa staining (X40). (B) Mutant peripheral blood shows a high proportion of nucleated erythroblasts (arrow) to enucleated erythroblasts (arrowhead) compared with (C) a wild-type littermate.

Copyright

This image is from Caruana G, PLoS One 2013;8(3):e55429, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199856

Associated Alleles

Symbol	Name
Lig1^m1Anu	ligase I, DNA, ATP-dependent; mutation 1, Australian National University

Associated Genotypes

Allelic Composition	Genetic Background
Lig1^m1Anu/Lig1^m1Anu	involves: C3H/HeH * C57BL/6JAnu