Phenotype Image Detail

Image

Caption

Urinary tract anomalies displayed by m2Anu/m2Anu (12BC-19), m3Anu/m3Anu (12BC-20) and m10Anu/m10Anu (14BC-07) lines.m3Anu/m3Anu (A-C). (A) Unilateral and (B) bilateral dilation of the renal pelvis (*). Kinks (A) and twisting (B) of the ureter (arrow) distal to the dilation. (C) Ureter bifurcation at the site marked with a line. Single ureter (arrow) below and bifurcated ureter (arrows) above the line. m2Anu/m2Anu (D-F). (D) Unilateral renal agenesis. (E) Bilateral hydronephrosis. (F) Bilateral hydroureter and hydronephrosis. m10Anu/m10Anu (G-I). (G) Dilated renal pelvis (*). (H) Duplicated ureter with hydroureter in one ureter leading to hydronephrosis in upper pole. (I) Unilateral renal hypoplasia (lines marking top and bottom of kidneys). a = adrenal, u = ureter.

Copyright

This image is from Caruana G, PLoS One 2013;8(3):e55429, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199856

Associated Alleles

Symbol	Name
m10Anu	mutation 10, The Australian National University
m2Anu	mutation 2, The Australian National University
m3Anu	mutation 3, The Australian National University

Associated Genotypes

Allelic Composition	Genetic Background
m2Anu/m2Anu	involves: C3H/HeH * C57BL/6JAnu
m3Anu/m3Anu	involves: C3H/HeH * C57BL/6JAnu
m10Anu/m10Anu	involves: C3H/HeH * C57BL/6JAnu