Phenotype Image Detail

Image

Caption

H&E-stained sections of colon from wild-type (WT) and Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw (mFPR2^-/-) mice treated with dextran sulfate sodium (DSS) for 5 days. Histological analysis showed that DSS treatment caused early recruitment of a significantly higher number of leukocytes, mainly neutrophils and macrophages, into the mucosal region of hte colon of wild-type mice compared with mutant mice. Scale bars: 25 um.

Copyright

This image is from Chen K, J Clin Invest 2013 Apr 1;123(4):1694-704 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:197568

Associated Alleles

Symbol	Name
Fpr2^tm1.2Jimw	formyl peptide receptor 2; targeted mutation 1.2, Ji Ming Wang

Associated Genotypes

Allelic Composition	Genetic Background
Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw	involves: 129X1/SvJ