Phenotype Image Detail

Image

Caption

Impaired epithelial restitution in the colons of Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw (mFPR2^-/-) mice in dextran sulfate sodium (DSS)-induced acute colitis. (A) H&E-stained sections of colon from mice treated with 5% DSS for 4 days followed by normal water for 4 days. Scale bars: 200 um and 100 um, respectively. (B) H&E-stained sections of colon from mice treated with 5% DSS for 4 days followed by normal water for 8 days. Arrows indicate ulcers. Scale bars: 100 um. (D) Ki67+-stained colonic crypts of mice treated with 5% DSS for 4 days followed by normal water for 1 day. Scale bars: 50 um. Ki67+ cells are shown in brown.

Copyright

This image is from Chen K, J Clin Invest 2013 Apr 1;123(4):1694-704 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:197568

Associated Alleles

Symbol	Name
Fpr2^tm1.2Jimw	formyl peptide receptor 2; targeted mutation 1.2, Ji Ming Wang

Associated Genotypes

Allelic Composition	Genetic Background
Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw	involves: 129X1/SvJ