Phenotype Image Detail

Image

Caption

Dextran sulfate sodium (DSS)-induced acute colon inflammation. Ascending colon from wild-type (WT) and Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw (mFPR2^-/-) littermates treated with 5% DSS for 4 days was sectioned (5 um) and stained with H&E. A-B. Injuries of crypts. C-D. Infiltration of leukocytes in the mucosa. E-F. Accumulation of leukocytes in the submucosa. N = 9 mice per group. Scale bar = 100 um (A-B) and 50 um (C-F), respectively.

Copyright

This image is from Chen K, J Clin Invest 2013 Apr 1;123(4):1694-704 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:197568

Associated Alleles

Symbol	Name
Fpr2^tm1.2Jimw	formyl peptide receptor 2; targeted mutation 1.2, Ji Ming Wang

Associated Genotypes

Allelic Composition	Genetic Background
Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw	involves: 129X1/SvJ