Phenotype Image Detail

Image

Caption

Impaired development of Sp2^tm1Sus/Sp2^tm1Sus (Sp2lzn/lzn) embryos. Homozygous mutant embryos at E18.5, E16.5 and E12.5 representing typical phenotypic variants. Homozygous mutant embryos at E12.5 have a normal body size but display hemorrhaging predominantly at the head.

Copyright

This image is from Baur F, PLoS One 2010;5(3):e9587, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158671

Associated Alleles

Symbol	Name
Sp2^tm1Sus	Sp2 transcription factor; targeted mutation 1, Guntram Suske

Associated Genotypes

Allelic Composition	Genetic Background
Sp2^tm1Sus/Sp2^tm1Sus	involves: 129P2/OlaHsd * C57BL/6