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Phenotype Image Detail
Image
Caption Absence of liver SLC2A2 (GLUT2) expression suppresses hepatic glucose uptake but does not impair endogenous glucose production. (A) PET imaging of 18FDG uptake by the liver and kidneys of control and Slc2a2tm2Thor/Slc2a2tm2Thor Albtm1(cre/ERT2)Mtz/Albtm1(cre/ERT2)Mtz (LG2KO) mice during the first 15 minutes after injection (dorsal view; red, high uptake; green, low uptake).
Copyright This image is from Seyer P, J Clin Invest 2013 Apr 1;123(4):1662-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:197607
Associated
Alleles
Symbol Name
Albtm1(cre/ERT2)Mtz albumin; targeted mutation 1, Daniel Metzger
Slc2a2tm2Thor solute carrier family 2 (facilitated glucose transporter), member 2; targeted mutation 2, Bernard Thorens
Associated
Genotypes
Allelic Composition Genetic Background
Albtm1(cre/ERT2)Mtz/Albtm1(cre/ERT2)Mtz
Slc2a2tm2Thor/Slc2a2tm2Thor
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory