Phenotype Image Detail

Image

Caption

Comparison of day 9.5 wild-type, heterozygous Dnm1l^Py/Dnm1l⁺ (Py/+) and homozygous Dnm1l^Py/Dnm1l^Py (Py/Py) embryos. Typical examples of individual fibroblasts obtained from culturing these embryos and stained with MitoTracker Orange are shown above. Below, typical examples of E9.5 embryonic fibroblasts in culture three days after embryo harvest. Note that the homozygous mutant cells have failed to proliferate and only a single cellis visible in this field.

Copyright

This image is from Ashrafian H, PLoS Genet 2010;6(6):e1001000, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:161510

Associated Alleles

Symbol	Name
Dnm1l^Py	dynamin 1-like; Python

Associated Genotypes

Allelic Composition	Genetic Background
Dnm1l^Py/Dnm1l^Py	involves: BALB/cAnNCrl * C3H/HeH