Phenotype Image Detail

Image

Caption

Histological overview of E7.5 and E8.5 Prkci^tm1.1Rfar/Prkci^tm1.1Rfar and wild-type embryos. Embryos were isolated at indicated time points and embedded in paraffin. (A) Sagittal sections of wild-type and mutant embryos at E7.5 (right). Phase contrast image of the corresponding embryo (left). (B) Sagittal sections of wild-type and mutant embryos at day E8.5 (right). Phase contrast image of the corresponding embryo (left). Abbreviations: ac, amniotic cavity; all, allantois; am, amnion; ec, ectoplacental cavity; fnf, forebrain neural-fold; hb, hindbrain; mb, midbrain; h, heart; ps, primitive streak; S = somites; tl; tiny lumina.

Copyright

This image is from Seidl S, PLoS One 2013;8(5):e62756, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:202124

Associated Alleles

Symbol	Name
Prkci^tm1.1Rfar	protein kinase C, iota; targeted mutation 1.1, Robert V Farese Sr

Associated Genotypes

Allelic Composition	Genetic Background
Prkci^tm1.1Rfar/Prkci^tm1.1Rfar	involves: 129P2/OlaHsd * BALB/cJ * NMRI