Phenotype Image Detail

Image

Caption

Haematoxylin and eosin staining showing epididymides of Nabp2^tm1.1Kkha/Nabp2^tm1.1Kkha Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺ (Ssb1^-/-) mice containing prematurely sloughed developing germ cells. The upper panel displays maturing spermatozoa in the wild-type epididymis. In contrast, immature germ cells (black arrow) are present in the epididymis of mutant mice (lower panel). Embedded images in the left corners show magnified views of the selected areas (Scale - 50 mm).

Copyright

This image is from Shi W, PLoS Genet 2013 Feb;9(2):e1003298, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195140

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm9(cre/ESR1)Arte	gene trap ROSA 26, Philippe Soriano; targeted mutation 9, TaconicArtemis
Nabp2^tm1.1Kkha	nucleic acid binding protein 2; targeted mutation 1.1, Kum Kum Khanna

Associated Genotypes

Allelic Composition	Genetic Background
Nabp2^tm1.1Kkha/Nabp2^tm1.1Kkha Gt(ROSA)26Sor^tm9(cre/ESR1)Arte/Gt(ROSA)26Sor^+	involves: C57BL/6 * C57BL/6NTac