Phenotype Image Detail

Image

Caption

Evidence of meningitis in Nlrp3^tm3.1Hhf/Nlrp3⁺ (NOMID) mice. Brains from P13 mice were stained with H&E. Mutant mice (B) showed a perivascular accumulation of neutrophils (arrows) in the meninges that is absent in wild-type (WT) mice (A).

Copyright

This image is from Bonar SL, PLoS One 2012;7(4):e35979, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:202147

Associated Alleles

Symbol	Name
Nlrp3^tm3.1Hhf	NLR family, pyrin domain containing 3; targeted mutation 3.1, Hal M Hoffman

Associated Genotypes

Allelic Composition	Genetic Background
Nlrp3^tm3.1Hhf/Nlrp3^+	involves: 129