Phenotype Image Detail

Image

Caption

Play MovieSerial 2D ECM image stack in the coronal plane of mutant (E14.5) reveals {A(I),A,D}, superior-inferior ventricles, double outlet right ventricle (DORV), atrioventricular septal defect (AVSD), common atrium, interrupted aortic arch (type C), hypoplastic pulmonary artery (PA), aberrant right subclavian artery forming incomplete vascular ring. Single lung lobe, left sided inferior vena cava (IVC), total anomalous pulmonary venous return (TAPVR), and left lung isomerism.

Copyright

This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Associated Alleles

Symbol	Name
Pcsk6^b2b2830Clo	proprotein convertase subtilisin/kexin type 6; Bench to Bassinet Program (B2B/CVDC), mutation 2830 Cecilia Lo