Phenotype Image Detail

Image

Caption

Adgrg6^tm1Taki/Adgrg6^tm1Taki (KO) E11.25 cardiomyocytes contain defective mitochondria. (A-C) Transmission electron micrographs displaying the ultrastructural details of cardiomyocytes in wild-type (WT) (A and C) and KO (B) hearts. (A) Mitochondria (Mi) with well-developed cristae (arrow) in WT cardiomyocytes. (B) KO cardiomyocytes contain abundant lipid droplets (Ld) and mitochondria with a more complex morphology, less well developed cristae, and electron-dense precipitates (arrowheads). (C) Glycogen (Gly) in WT cardiomyocytes. (Scale bar: 1 um).

Copyright

This image is from Patra C, Proc Natl Acad Sci U S A 2013 Oct 15;110(42):16898-903. Copyright 2013 National Academy of Sciences, U.S.A. J:202002

Associated Alleles

Symbol	Name
Adgrg6^tm1Taki	adhesion G protein-coupled receptor G6; targeted mutation 1, Tetsu Akiyama

Associated Genotypes

Allelic Composition	Genetic Background
Adgrg6^tm1Taki/Adgrg6^tm1Taki	involves: C57BL/6