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Phenotype Image Detail
Image
Caption Dietary challenge with high protein diet in Mmuttm1Cpv/Mmuttm1Cpv Tg(Alb-Mut)#Cpv/0 (Mut-/-;TgINS-Alb-Mut) mice. (A) Transmission EM showed enlarged mitochondria with whorl-likecristae (Aa vs. Ab; white arrows, mitochondria; white asterisks, brush border of the proximal tubule). Glomeruli appeared normal (Ac and Ad; white asterisks, podocyte foot processes).
Copyright This image is from Manoli I, Proc Natl Acad Sci U S A 2013 Aug 13;110(33):13552-7. Copyright 2013 National Academy of Sciences, U.S.A. J:200689
Associated
Alleles
Symbol Name
Mmuttm1Cpv methylmalonyl-Coenzyme A mutase; targeted mutation 1, Charles P Venditti
Tg(Alb-Mut)#Cpv transgene insertion, Charles P Venditti
Associated
Genotypes
Allelic Composition Genetic Background
Mmuttm1Cpv/Mmuttm1Cpv
Tg(Alb-Mut)#Cpv/0 		involves: C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory