Phenotype Image Detail

Image

Caption

Inner ears of control and Lmx1a^dr-10J/Lmx1a^dr-10J mice. (A, B) H&E stained cross-sections (4 um) of inner ears from a heterozygous (A) and a homozygous Lmx1a^dr-10J (B) adult. (C) Whole mount preparation of inner ears from a heterozygous control mouse (left) and a homozygous mutant (right) viewed by light microscopy. Brackets identify the cochlea (Co) and vestibular apparatus (V). Arrows indicate the utricle (U) saccule (S) and semi-circular canals (Sc). These compartments are malformed and underdeveloped in the mutant homozygous ear (B, C-right).

Copyright

Photo courtesy of Mouse Mutant Resource at the Jackson Laboratory. https://www.jax.org/research-and-faculty/tools/mouse-mutant-resource J:110244

Associated Alleles

Symbol	Name
Lmx1a^dr-10J	LIM homeobox transcription factor 1 alpha; dreher 10 Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Lmx1a^dr-10J/Lmx1a^dr-10J	129P3/J-Lmx1a^dr-10J/J