Phenotype Image Detail

Image

Caption

Microcomputed tomography and parameters of trabecular bone in the distal femurs (D) and fourth vertebrae (E) in wild-type, Htra1^tm1.1Pfi heterozygous (HET), and Htra1^tm1.1Pfi/Htra1^tm1.1Pfi (KO) mice (all males, 3 months old). For both (D) and (E), *P<0.05. **P<0.01, ***P<0.001, ANOVA and Fisher's protected least significant difference test, n=13.

Copyright

This image is from Graham JR, PLoS One 2013;8(9):e74094, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:206395

Associated Alleles

Symbol	Name
Htra1^tm1.1Pfi	HtrA serine peptidase 1; targeted mutation 1.1, Pfizer, Ltd

Associated Genotypes

Allelic Composition	Genetic Background
Htra1^tm1.1Pfi/Htra1^tm1.1Pfi	involves: 129S/SvEv