Phenotype Image Detail

Image

Caption

Retardation of retinal vascular growth in Arhgef15^tm1Nmoc/Arhgef15^tm1Nmoc (Arhgef15^lacZ/lacZ) mouse. (A) Whole-mount IHC for PECAM-1 in P5 and P8 retinas. Circles represent the vascular margin of the wild-type (Arhgef15^WT/WT) retinas. (B) Quantification of the radius of the retinal vascular networks (P5, n = 6; P8, n = 4). (C) Morphometric analyses of vascular networks in P5 retinas (n = 6 per group). Scale bar: 200 um. Error bars represent SEM; *P<0.05, **P<0.01.

Copyright

This image is from Kusuhara S, PLoS One 2012;7(9):e45858, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191977

Associated Alleles

Symbol	Name
Arhgef15^tm1Nmoc	Rho guanine nucleotide exchange factor 15; targeted mutation 1, Naoki Mochizuki

Associated Genotypes

Allelic Composition	Genetic Background
Arhgef15^tm1Nmoc/Arhgef15^tm1Nmoc	B6.Cg-Arhgef15^tm1Nmoc