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Caption | A, histology of the femoral condyle shows defects in secondary ossification in a 40-week old Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul (LBeta3/LBeta3) mouse. B, representative microcomputed tomography colored images from younger mutant and wild-type mice (14 weeks old) confirm the defects seen in the histology. The intensity of color in the images is indicative of mineral density where the color scale represents the grayscale pixel density. C, osteocalcin staining for osteoblasts. Tibias from the wild-type (+/+) mice show recruitment of osteoblasts to the trabecular bone, whereas the numbers of osteoblasts is decreased on the trabecular bone of the mutant mice. Mice were about 40 weeks old. | ||||
Copyright | This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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