Phenotype Image Detail

Image

Caption

C, adipose tissue underlying the skin dermis is reduced in an aged 15-week-old Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul} (LBeta3/LBeta3) mouse. D, Mutant mice do not develop steatosis as wild-type (+/+) mice as seen with H&E (40 weeks) and Oil Red O (17 weeks) staining. E, adipocyte size is reduced in the mutant mice.

Copyright

This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892

Associated Alleles

Symbol	Name
Tgfb1^tm1(Tgfb3)Kul	transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni

Associated Genotypes

Allelic Composition	Genetic Background
Tgfb1^tm1(Tgfb3)Kul/Tgfb1^tm1(Tgfb3)Kul	involves: 129S1/Sv * 129X1/SvJ * C57BL/6