Phenotype Image Detail

Image

Caption

Advanced skeletal muscle development in Capn6^tm1Hiso/Capn6^tm1Hiso (Capn6^lacZ/lacZ) embryos. (A-D) X-gal-stained coronal sections of the tongue of an E16.5 Capn6^tm1Hiso/Capn6⁺ (Het) (A, C) and Capn6^tm1Hiso/Capn6^tm1Hiso (Ho) (B, D) embryo. The boxed areas in A and B are enlarged in C and D, respectively. Scale bar: 50 um. (E) The average diameter of tongue muscle fibers was measured in the anterior region of coronal sections. The average diameter was significantly larger in homozygotes (9.13 [mean] +/-0.56 [s.e.m.] um, n = 5) than in heterozygotes (5.64 +/- 0.23 um, n = 5). **, P < 0.01 by Student's t-test.

Copyright

This image is from Tonami K, PLoS Genet 2013 Aug;9(8):e1003668, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200747

Associated Alleles

Symbol	Name
Capn6^tm1Hiso	calpain 6; targeted mutation 1, Hiroyuki Sorimachi

Associated Genotypes

Allelic Composition	Genetic Background
Capn6^tm1Hiso/Capn6^tm1Hiso	B6.Cg-Capn6^tm1Hiso