Phenotype Image Detail

Image

Caption

Histological analysis of tongue muscle of E16.5 Capn6^tm1Hiso/Capn6⁺ (Capn6^lacZ/+; Het) female and Capn6^tm1Hiso/Capn6^tm1Hiso (Capn6^lacZ/lacZ; Ho) female embryos. (A, B) Low magnification images of the tongue coronal sections shown in Figure 3A-D. Scale bar: 500 um. (C) Coronal X-gal-stained sections of the tongue's posterior region. Scale bar: 50 um. (D) Average diameter of tongue muscle fibers in the posterior region (the areas in boxes a" and b"; for boxes a' and b', see Figure 3E) of coronal sections. The average diameter was significantly larger in the homozygote (7.50 [mean]+/-0.73 [s.e.m.] um; n= 5) than in the heterozygote (5.46+/-0.89 um; n= 5). **, P < 0.01 by Students t-test. The results for boxes a' and b' are shown in Figure 3E.

Copyright

This image is from Tonami K, PLoS Genet 2013 Aug;9(8):e1003668, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200747

Associated Alleles

Symbol	Name
Capn6^tm1Hiso	calpain 6; targeted mutation 1, Hiroyuki Sorimachi

Associated Genotypes

Allelic Composition	Genetic Background
Capn6^tm1Hiso/Capn6^tm1Hiso	B6.Cg-Capn6^tm1Hiso