Phenotype Image Detail

Image

Caption

Histological analysis of the femure of wild-type (Shn^+/+) and Hivep3^tm2Glm/Hivep3^tm2Glm (Shn3^KI/KI) mice. Hemotoxylin and eosin-stained sections through the proximal femur of 8 week old mice, showing an increase in bone mass (top). TRAP staining of the trabecular bone below the growth plate of the tibia in 8 week old wild-type and mutant mice (bottom). TRAP-positive osteoclasts stain a magenta color.

Copyright

This image is from Shim JH, J Clin Invest 2013 Sep 3;123(9):4010-22 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201597

Associated Alleles

Symbol	Name
Hivep3^tm2Glm	human immunodeficiency virus type I enhancer binding protein 3; targeted mutation 2, Laurie H Glimcher

Associated Genotypes

Allelic Composition	Genetic Background
Hivep3^tm2Glm/Hivep3^tm2Glm	involves: C57BL/6