Phenotype Image Detail

Image

Caption

Scanning electron microscopy images of the aortic valve of a wild-type (WT) littermate (left) and a Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (XS homo) homozygote with aortic valvular stenosis (right). Note marked thickening of the valve leaflets of the mutant.

Copyright

This image is from Kelsey L, PLoS Genet 2013;9(7):e1003612, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:206507

Associated Alleles

Symbol	Name
Klf3^Gt(XS0187)Wtsi	Kruppel-like transcription factor 3 (basic); gene trap XS0187, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Klf3^Gt(XS0187)Wtsi/Klf3^Gt(XS0187)Wtsi	involves: 129P2/OlaHsd * C57BL/6