Phenotype Image Detail

Image

Caption

Pulmonary valve histology at low power (C) for wild-type (WT) mice (left), Klf3^{Gt(XS0187)Wtsi}/Klf3^{Gt(XS0187)Wtsi} (XS - middle) and Klf3^{Gt(CH0516)Wtsi}/Klf3^{Gt(CH0516)Wtsi} (CH - right). (D) Higher power images of the pulmonary valves located in the boxed regions in (C). Pulmonary valve leaflets were often abnormally thickened in XS and CH mutants (arrows).

Copyright

This image is from Kelsey L, PLoS Genet 2013;9(7):e1003612, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:206507

Associated Alleles

Symbol	Name
Klf3^Gt(CH0516)Wtsi	Kruppel-like transcription factor 3 (basic); gene trap CH0516, Wellcome Trust Sanger Institute
Klf3^Gt(XS0187)Wtsi	Kruppel-like transcription factor 3 (basic); gene trap XS0187, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Klf3^Gt(XS0187)Wtsi/Klf3^Gt(XS0187)Wtsi	involves: 129P2/OlaHsd * C57BL/6
Klf3^Gt(CH0516)Wtsi/Klf3^Gt(CH0516)Wtsi	involves: 129P2/OlaHsd * C57BL/6