Phenotype Image Detail

Image

Caption

Increased neutrophil but slightly decreased macrophage infiltration of wounds in Hspb1^tm1.1Jdn/Hspb1^tm1.1Jdn (hspB1^del/del) mice. A, Neutrophil infiltration in d1 wound granulation tissue assessed by IHC for neutrophil elastase (NE) and macrophage infiltration at d3 detected by F4/80 staining. B, Plot shows elastase positive neutrophils (NE+) per high power field (hpf); 7 fields/wound; 2 wounds per mouse; n = 4 mice; **P<0.01. C, Plot as for (B) showing F4/80-positive cells/hpf; *P<0.05.

Copyright

This image is from Crowe J, PLoS One 2013;8(10):e77383, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:209117

Associated Alleles

Symbol	Name
Hspb1^tm1.1Jdn	heat shock protein 1; targeted mutation 1.1, Jonathan Dean

Associated Genotypes

Allelic Composition	Genetic Background
Hspb1^tm1.1Jdn/Hspb1^tm1.1Jdn	B6.129S2(Cg)-Hspb1^tm1.1Jdn