Phenotype Image Detail

Image

Caption

Dcbld2 (Esdn) modulates developmental angiogenesis in mice. Retinal angiogenesis in Dcbld2^tm1.1Mhms/Dcbld2^tm1.1Mhms (Esdn-/-) mice. Representative examples (A) and quantification in the entire retina (B and C) of isolectin staining of blood vessels in wild-type (WT) and mutant mice on postnatal day 5. n = 12. Scale bars: 500 um, upper panels; 100 um, lower panels. (D and E) Retinal pericyte staining. Representative examples (D) and quantification (E) of NG2 immunostaining of retinal blood vessels in WT and mutant mice on postnatal day 5. n = 6. Scale bars: 50 um

Copyright

This image is from Nie L, J Clin Invest 2013 Dec 2;123(12):5082-97 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:207629

Associated Alleles

Symbol	Name
Dcbld2^tm1.1Mhms	discoidin, CUB and LCCL domain containing 2; targeted mutation 1.1, Mehran M Sadeghi

Associated Genotypes

Allelic Composition	Genetic Background
Dcbld2^tm1.1Mhms/Dcbld2^tm1.1Mhms	B6.129S6-Dcbld2^tm1.1Mhms