Phenotype Image Detail

Image

Caption

Neuropathology in Tg(Prnp-SNAP25/HTT*150Q)8Xjl/0 (150Q) transgenic mouse brain. (A) GFAP immunocytochemical staining shows an increase in the density of GFAP-positive glial cells in the striatum, white matter (corpus callosum), and cerebellum of Tg(Prnp-SNAP25/HTT*150Q)8Xjl/0 mice at 1 year of age compared with wild-type (WT) and SNAP25-20Q mice. Bar, 100 um.

Copyright

This image is from Xu Q, J Cell Biol 2013 Sep 30;202(7):1123-38, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:201806

Associated Alleles

Symbol	Name
Tg(Prnp-SNAP25/HTT*150Q)8Xjl	transgene insertion 8, Xiao-Jiang Li

Associated Genotypes

Allelic Composition	Genetic Background
Tg(Prnp-SNAP25/HTT*150Q)8Xjl/0	involves: FVB