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Phenotype Image Detail
Image
Caption Cell death is enhanced, and regeneration is blunted in cardiotoxin (CTX)-injured mice with knockout of skeletal muscle-specific Cygb. (A) H&E staining demonstrated delayed regeneration in Cygbtm1Ppam/Cygbtm1Ppam Tg(Myog-cre)1Eno/0 muscle 14 days after CTX injury. Note the persistence of centrally nucleated myocytes (evidence of ongoing muscle regeneration) in the mutant muscle. (Scale bar: 40 um).
Copyright This image is from Singh S, Proc Natl Acad Sci U S A 2014 Jan 7;111(1):E129-38. Copyright 2014 National Academy of Sciences, U.S.A. J:206378
Associated
Alleles
Symbol Name
Cygbtm1Ppam cytoglobin; targeted mutation 1, Pradeep PA Mammen
Tg(Myog-cre)1Eno transgene insertion 1, Eric N Olson
Associated
Genotypes
Allelic Composition Genetic Background
Cygbtm1Ppam/Cygbtm1Ppam
Tg(Myog-cre)1Eno/0 		involves: 129 * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory