Phenotype Image Detail

Image

Caption

External views of E18.5 Dhrs3^{tm1(NCOM)Mfgc}/Dhrs3^{tm1(NCOM)Mfgc} mouse embryos. Null mutants have a noticeably different appearance compared to wild-type littermates, with smaller eyes, unfused eyelids, and a very prominent and consistent cleft palate. Arrow indicates clefting of the secondary palate.

Copyright

This image is from Adams MK, J Biol Chem 2014 May 23;289(21):14868-80 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:214109

Associated Alleles

Symbol	Name
Dhrs3^tm1(NCOM)Mfgc	dehydrogenase/reductase 3; targeted mutation 1, Mammalian Functional Genomics Centre
Dhrs3^tm1(NCOM)Mfgc	dehydrogenase/reductase 3; targeted mutation 1, Mammalian Functional Genomics Centre

Associated Genotypes

Allelic Composition	Genetic Background
Dhrs3^tm1(NCOM)Mfgc/Dhrs3^tm1(NCOM)Mfgc	involves: C57BL/6 * C57BL/6N