Phenotype Image Detail

Image

Caption

Histology of bone from wild-type and Snx10^{tm1a(EUCOMM)Raba}/Snx10^{tm1a(EUCOMM)Raba} mice. Low magnification of Von Kossa/van Gieson staining (A and B) of femur longitudinal sections from 3 week-old mice demonstrate endosteum filled with unresorbed cartilage (purple stained trabecular cores) and thin cortical bone (black arrowheads) in mutant mice. (B) Higher magnification (C and D) reveals non-mineralized osteoid (pink-stained surface, indicated with asterisks), covering the mineralized trabeculae (black) from mutant bones (D). Bar = 0.05 mm.

Copyright

This image is from Ye L, PLoS Genet 2015 Mar;11(3):e1005057, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:224711

Associated Alleles

Symbol	Name
Snx10^tm1a(EUCOMM)Raba	sorting nexin 10; targeted mutation 1a, Ricardo A Battaglino

Associated Genotypes

Allelic Composition	Genetic Background
Snx10^tm1a(EUCOMM)Raba/Snx10^tm1a(EUCOMM)Raba	involves: 129S4/SvJae * C57BL/6 * C57BL/6J