Image |
|
||||
Caption | Histological and whole-mount neuromuscular analysis of Ednratm6(Edn1)Hku/Ednra+ (EdnraEdn1/+) mice. (A and B) Frontal sections of E18.5 wild-type (WT) (A) and mutant (B) mice stained by Mallory trichromic. Constitutive activation of Edn1/Ednra signaling results not only in the transformation of maxillary skeletal elements, but also in the appearance of new muscular components associated to the ectopic dentary, which can be interpreted as a duplicated masseter muscle. (C and D) Cranial nerves of E10.5 WT (C) and mutant (D) embryos stained by antineurofilament antibody. Ectopic branches of the mandibular (arrow) and facial (arrowheads) nerves are indicated. dnt, dentary; mm, masseter muscle; pl, palatine; tg, tongue; gV, trigeminal ganglion; V1, ophthalmic nerve; V2, maxillary nerve; V1, mandibular nerve; VII, facial nerve; IX, glossopharyngeal nerve; *, ectopic structure. | ||||
Copyright | This image is from Sato T, Proc Natl Acad Sci U S A 2008 Dec 2;105(48):18806-11. Copyright 2008 National Academy of Sciences, U.S.A. J:224515 | ||||
Associated Alleles |
|
||||
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/17/2024 MGI 6.24 |
![]() |
|