Phenotype Image Detail

Image

Caption

Lateral and caudal views of E18.5 wild-type (WT) and Ednra^tm6(Edn1)Hku/Ednra⁺ (Ednra^Edn1/+) cranio-facial skeletons with schematic representations. The maxillary and mandibular elements are in yellow and red, respectively. Transformed parts of the maxillary structures are colored with orange. at, ala temporalis; bs, basisphenoid; dnt, dentary; etm, ectotympanic; fmx, frontal process of maxilla; gn, gonial; hy, hyoid; in, incus; jg, jugal; la, lacrimal; lo, lamina obturans; ma, malleus; MC, Meckel's cartilage; mx, maxilla; pl, palatine; pmx, premaxilla; ptg, pterygoid; sp, styloid process; sq, squamosal; st, stapes; *, ectopic structure.

Copyright

This image is from Sato T, Proc Natl Acad Sci U S A 2008 Dec 2;105(48):18806-11. Copyright 2008 National Academy of Sciences, U.S.A. J:224515

Associated Alleles

Symbol	Name
Ednra^tm6(Edn1)Hku	endothelin receptor type A; targeted mutation 6, Hiroki Kurihara

Associated Genotypes

Allelic Composition	Genetic Background
Ednra^tm6(Edn1)Hku/Ednra^+	involves: 129 * C57BL/6 * ICR